# | Baxter R | Martin JL | | | | | | | | | Structure of the Mr 140,000 growth hormone-dependant insulin-like growth factor binding protein complex: Determination by reconstitution and affinity labelling. | Proc Natl Acad Sci | 86 | 6898-6902 | 1989 | BP | igf | method | | | detailed strutural analysis of IGF-BP 150. GH dependant. Alpha, beta and gamma (IGF) subunits. | etal_off | research | copy_on
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1 | Dawson TP | Gandhi R | LeHir M | Kaissling B | | | | | | | Ecto-5‘-Nucleotidase: Localization in the Rat Kidney by Light Microscopic Histochemical and Immunohistochemical Methods. | J Histochem Cytochem | 37 | 39–47 | 1989 | renal | | | | | Possible mechs of Glom/Tubeule feedback. | etal_off | research | copy_on |
2 | Wilkins J | D'Ercole AJ | | | | | | | | | Affinity labelled plasma somatomedin-C/insulin like growth factor I binding protein. Evidence of growth hormone dependence and subunit structure. | J Clin Invest | 75 | 1350-1358 | 1985 | igf | method | | | | Original work on DSS crosslinking and PAGE. | etal_off | research | copy_on |
3 | Adams SO | Kapadia M | Mills B | Daughaday WH | | | | | | | Release of insulin-like growth factors and binding protein activity into serum-free medium of cultured human fibroblasts. | Endocrinol | 115 | 520-526 | 1984 | igf | method | | | | Acid/EtOH & gel extraction. Contradicting previous paper, believes that acid strip NOT enough. Confusing HPLC results. Binding protein assay with DSS. | etal_off | research | copy_on |
4 | Unterman TG | Patel K | Kumar Mahathre V | Rajamohan G | | | | | | | Regulation of Low Molecular Weight Insulin-Like Growth Factor Binding Proteins in Experimental Diabetes Mellitus. | Endocrinol 1990b | 126(5) | 2614 | 1990 | igf | bp | | | | BP assay with Charcoal, ref and method. Problem with stripping off IGF. Good range of methodologies, ligand blots, DSS affinity labelling, Neutral gel analysis. | etal_off | research | copy_on |
5 | Wang JF | Hampton B | Mehleman T | Burgess WH | Rechler M | | | | | | Isolation of a Biologically active fragment from the carboxy terminus of the fetal rat binding protein for insulin-like growth factors. | Biochem Biophys Res Comms | 157(2) | 718-726 | 1988 | bp | method | | | | Methods, BP ligand assay c charcoal. CM 2-3 litres. Dialysis vs 0.1M AA. DSS X-link method. Possible that 14k fragment would be difficult to separate off on column. | etal_off | research | copy_on |
6 | Lamson G | Oh Y | Pham H | Giudice LC | Rosenfeld RG | | | | | | Expression of two insulin like growth factor binding proteins in a Human endometrial cancer cell line: Structural, Immunological and Genetic characterization. | J Clin Endo Metab | 69(4) | 852 | 1989 | bp | igf | | | | Good coverage of the FIVE BPs & actions. Differential glycosylation ->apparent diff MWs. Amniotic fluid-hBP25- inhibits mitogenic action ofIGF. ?Paracine action of BP modulating IGF action. Methods - Westernblots. | etal_off | review | copy_off |
7 | Dawson TP | Wyllie FS | Wynford-Thomas D | | | | | | | | In Vitro Responsiveness to Serum Growth Factors is inversely related to in vivo malignancy in human thyroid epithelial cells. | Br J Cancer | 63 | 897–900 | 1991 | GFs | thyroid | | | | A paradox....? | etal_off | research | copy_on |
8 | Hossenlopp P | Seurin D | Segovia-Quinson B | Hardouin S | Binoux M | | | | | | Analysis of Serum insulin like growth factor binding proteins using Western Blotting: Use of the method for titration of the Binding Proteins and competative binding studies. | Anal Biochem | 154 | 138-143 | 1986 | method | bp | | | | Original Ligand blotting method as used by Zapf. | etal_off | research | copy_off |
9 | Blum WF | Jenne EW | Reppin F | Keitzzman K | Ranke MB | Bierich JR | | | | | Insulin-like growth factor I (IGF-I)- binding protein complex is a better mitogen than free IGF-I | Endocrinol | 125 | 766-772 | 1989 | igf | rate | | | | Secretion rate of IGF - BHK 7.5/HSF 24 mg/24hrs/million cells. IGF ata low continuous level promotes mitogenesis. Kd of receptor and BP similar therefore supplies at just right rate. Good description of receptor internalization. Equilibrium explains why | etal_off | research | copy_off |
10 | Zapf J | Schmid Ch | Guler HP | | | | | | | | Regulation of binding proteins for insulin-like growth factors (IGF) in humans. Increased expression of IGF binding protein 2 during IGF 1 treatment of healthy adults and patients with extrapancreatic tumour. | J Clin Invest | 86 | 952-961 | 1990 | bp | igf | | | | Hossenlopp's ligand blotting method described. Summary of normal serum binding proteins. Hypothesis on regulation of insulin like effects of IGF by localization effects of BPs intravascularly. | etal_off | research | copy_off |
11 | Unterman TG | Oehler DT | Gotway MB | Harris PW | | | | | | | Production of the rat type I insulin-like growth factor binding protein by well differentiated H4EIIC3 hepatoma cells: identification, purification and N-terminal amino acid analysis. | Endocinol 1990a | 127(2) | 789-797 | 1990 | hepatoma | igf | | | | BP assay with PEG and ligand blotting | etal_off | research | copy_off |
12 | Bachrach LK | Tram T | Goretski P | | | | | | | | Insulin like growth factors and their binding proteins in human thyroid follicular carcinoma cells. | California IGF Meeting Abstracts | | 1991 | | thyroid | igf | bp | | | Gives nebulous figures for production NOT as per cell. FTC 133 & 236 produce minimal IGF but abundant IGF BPs. | etal_off | research | copy_off |
13 | Mohan S | Bautista CM | Wergedal J | Baylink D | | | | | | | Isolation of an inhibitory insulin-like growth factor (IGF) binding protein from bone cell-conditioned medium: A potential local regulator of IGF action. | Proc Natl Acad Sci | 86 | 8338-8342 | 1989 | bp | igf | | | | Refs to inhibitory actions of BPs. DSS crosslinking studies. Inhibitory IGF BP found from osteosarcoma cells. Discussion contains good review of inhibitory/stimulatory effects of BPs | etal_off | research | copy_off |
14 | Minuto F | Barreca A | Del Monte P | Cariola A | | | | | | | Immunoreactive insulin-like growth factor I (IGF-I) and IGF-I-binding protein content in human thyroid tissue. | J Clin Endocrinol Metab | 68(3) | 621-626 | 1989 | | igf | | | | Norm and MNG studied. Tissue and plasma levels of IGF. Stimulatory effect of TSH is mediated by IGF. IGF levels in MNG>norm. IGF stimulates other GF production - refs. Though no evidence of EGF production. | etal_off | research | copy_off |
15 | Gelato MC | Gaynes LA | Greenstein | Nissley SP | | | | | | | Heterogeneity of binding subunits of the human 150k insulin-like growth factor binding protein. | J Clin Endocrin Metab | 70(4) | 879-887 | 1990 | | bp | | | | further evidence for 150k BP made up of multiple subunits with different affinities for IGFs 1 & 2. | etal_off | research | copy_off |
16 | Lee CY | Henricks DM | | | | | | | | | Comparisons of various acidic treatments of bovine serum on insulin-like growth factor-I immunoreactivity and binding activity. | J Endocrinol | 127 | 139-148 | 1990 | | methods | | | | No abstract available | etal_off | review | copy_on |
17 | Conver CA | | | | | | | | | | Potentiation of insulin-like growth factor (IGF) action by IGF bindingprotein-3: Studies of the underlying mechanism. | Endocrinol | 130 | 3191-3199 | 1992 | igf | bp3 | | | | | etal_off | research | copy_off |
18 | Liu F | Powell DR | Hintz RL | | | | | | | | Characterization of insulin-like growth factor binding proteins in human serum from patients with chronic renal failure. | J Clin Endocrinol | 70 | 620-628 | 1990 | | | | | | | etal_off | research | copy_off |
19 | Drop SLS | | | | | | | | | | On the nomenclature of the insulin-like growth factor binding proteins. | Mol Cell Endocrinol | 67 | 243-244 | 1989 | bp | | | | | Good review | etal_off | review | copy_on |
20 | Baxter RC | | | | | | | | | | Circulating levels and molecular distribution of the acid-labile subunit of the high molecular weight insulin-like growth factor-binding protein complex. | J Clin Endocrinol Metab | 70 | 1347-1353 | 1990 | method | bp | | | | 150kDa BP has 3 subunits. More info on the beta (binding) unit. | etal_off | research | copy_off |
21 | Brinkman A | Groffen C | Kortleve DJ | van Kessel AG | Drop SLS | | | | | | Isolation and characterisation of a cDNA encoding the low molecular weight insulin-like growth factor binding protein (IBP-1). | EMBO J | 7 | 2417-2423 | 1988 | bp | receptors | | | | Fetal IGF-BP MW 30kDa, notes on receptor affinities. | etal_off | research | copy_on |
22 | Blat C | Delbe J | Villaudy J | Chatelain G | Golde A | Harel L | | | | | Inhibitory diffusible factor 45 bifunctional activity. | J Bio Chem | 264 | 12449-1245 | 1989 | | bp | | | | ?? inhibitory BP - 45 kDa. | etal_off | research | copy_off |
23 | Hill DJ | Camacho-Hubner C | Rashid P | Strain AJ | Clemmons DR | | | | | | Insulin-like growth factor (IGF)-binding protein release by human fetal fibroblasts: dependency on cell density and IGF peptides. | J Endocrinol | 122 | 87-98 | 1989 | bp | fibroblast | | | | Exogenous IGF stimulates BP production. Sparse cultures release more IGF than confluent. Insulin and hPL cause IGF release. | etal_off | research | copy_on |
24 | Martin JL | Baxter RC | | | | | | | | | Insulin-like growth factor-binding protein from human plasma: purification and characterization. | J Biol Chem | 261 | 8754-8760 | 1986 | igf | method | | | | More evidence for 26-22 kDa BP subunits of 150 kDa BP | etal_off | research | copy_on |
25 | Reeve JG | Payne JA | Bleehen NM | | | | | | | | Production of immunoreactive insulin growth factor-I (IGF-I) and IGF-I binding proteins by human lung tumours. | Br J Cancer | 61 | 727-731 | 1990 | lung | method | | | | Acid/EtOH strip. Commercial RIA (Amersham), immunoradiometric assay, binding protein assay-PAGE with DSS cross-linking. | etal_off | research | copy_off |
26 | Wang JF | Becks GP | Buckingham KD | Hill DJ | | | | | | | Characterization of insulin-like growth factor binding proteins secreted by isolated sheep thyroid epithelial cells. | J Endocrinol | 125 | 439-448 | 1990 | thyroid | bp | | | | Good intro. Cultures prod IGF - ref. Methods for BP study - Ligand blot, s-200 gel etc. 10^5 cells in a 24 well dish. NB - acid gel chromatography denatures BP 46 & 30 -> V0 assay NOT accurate. | etal_off | research | copy_on |
27 | Dawson TP | James R | Williams GT | | | | | | | | Silicone Plastinated Pathology specimens and their teaching potential. | J Path | 162 | 265–272 | 1990 | | teaching | | | | Plastination as an alternative to formalin fixation. | etal_off | research | copy_on |
28 | Wyllie FS | Dawson TP | Bond J et al | | | | | | | | Correlated abnormalities of TGF-ß response and p53 structure/expression in thyroid epithelial cell transformation. | Mol Cell Endocrinol | 76 | 13–21 | 1991 | icc | | | | | ICC & TC paper | etal_off | research | copy_on |
29 | Bond J | Dawson TP | Wynford-Thomas D | | | | | | | | Effect of Serum Growth Factors and Phorbol Esters on Growth and survival of Human Thyroid Epithelial Cells expressing Mutant ras. | Mol Carcinogenesis | 5 | 129–135 | 1991 | TPA | ras | | | | A cure for cancer !! | etal_off | research | copy_on
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